Your First Month on Weight Loss Injections: What to Expect
A guide to physical changes, dosage progression, and staying motivated in your first month.
Starting your journey with weight loss injections can feel exciting yet overwhelming. Whether you’re using a GLP-1 medication like Wegovy or another prescription weight loss option, the first month is all about learning how your body responds, building healthy habits, and staying motivated.
At MediClick Pharmacy, we’re here to support your progress every step of the way with a UK-registered prescription process, discreet next-day delivery, and ongoing weight loss support.

What to Expect in the First Month of Weight Loss Injections
1. Dosage Progression: Starting Slow for Lasting Success
GLP-1 injections such as Wegovy start with a low initial dose that gradually increases over several weeks. This starter plan helps your body adjust while reducing the risk of injection side effects like nausea, bloating, or fatigue.
Most patients begin with a once-weekly injection, moving up through a tiered dose plan over the first 4-5 weeks. Always follow your prescriber’s instructions to ensure safe and effective progression.
2. Appetite Changes and Early Results
One of the first changes you may notice is a reduction in appetite. This is how GLP-1s work by slowing digestion and helping you feel fuller for longer. During this time, focus on:
- Eating smaller portions
- Drinking plenty of water
- Choosing high-fibre, nutrient-dense foods
Some users see early weight loss results with injections in the first 2-4 weeks, but remember, everyone’s journey is different.
3. Managing Injection Side Effects
The goal is long-term, sustainable weight loss.Common injection side effects in the first month include:
- Nausea
- Constipation
- Headaches
- Mild fatigue
These typically settle as your body adjusts to the medication. Eating slowly and avoiding greasy or sugary foods can help ease symptoms.
If side effects persist or worsen, contact your prescriber for advice. With MediClick, you have access to UK-based clinical support throughout your treatment.
4. Staying Motivated and On Track
The first month is as much mental as physical. Build positive habits early:
- Track your meals, water intake, and mood
- Celebrate small milestones
- Stay active, even if it’s just a daily walk
- Reach out for encouragement or weight loss support if needed at Mediclick Pharmacy.
5. Creating a Healthy Daily Routine
MediClick’s team is always here to help you stay focused on your goals. Alongside your injections, developing a structured daily routine can reinforce your progress. Set consistent meal times, get adequate sleep, and schedule time for gentle physical activity. GLP-1 medications work best when combined with mindful lifestyle changes. This structure not only enhances results but also gives you a strong foundation for future months.
6. Tracking Your Progress and Setting Goals
Keeping a journal or using a health app to track your progress during the first month can help maintain motivation and provide a clearer picture of what’s working. Whether it’s changes in appetite, clothing fit, or energy levels, celebrating non-scale victories is equally important. Set realistic weekly goals to keep yourself accountable without pressure.
7. Understanding Emotional Changes
It’s completely normal to experience a mix of emotions as your routine shifts. Some users report feeling more in control, while others find adjusting to appetite changes challenging. Acknowledge your feelings and lean on your support network, whether it’s friends, family, or our expert team at MediClick. Emotional resilience is key to long-term weight management.
FAQs: First Month on GLP-1 Injections
What are the typical changes during the first month of a weight loss plan?
You may notice appetite reduction, smaller portion sizes, and mild side effects like nausea or fatigue.
How quickly do weight loss injections start to work?
Some people see results in 2-4 weeks, though this varies. Focus on building consistent habits for long-term success.
Are injection side effects normal in the beginning?
Yes, most side effects are mild and temporary. Gradual dose increases help minimise discomfort.
What support does MediClick offer?
We provide UK-regulated consultations, treatment plans, and continuous weight loss support throughout your journey.
Do I need a prescription for weight loss injections?
Yes, these treatments require a prescription. You can complete a secure consultation with our UK prescribers online.
Why Choose MediClick Pharmacy?
- GPhC-registered UK online pharmacy
- Trusted access to prescription weight loss treatments like Wegovy
- Safe consultations with UK prescribers
- Discreet packaging and next-day delivery
- Tailored starter plans with ongoing support

Ready to Begin?
Your first month is a powerful start toward a healthier you. With the right support, realistic goals, and expert guidance, you can make real progress.
Order your prescription weight loss starter plan securely online with MediClick Pharmacy today.