Nytol One-A-Night

Nytol One-A-Night

£6.90

Key Points

  • Contains diphenhydramine 50mg
  • Helps you fall asleep faster and stay asleep longer
  • For short-term use only
  • One tablet per night – no repeat doses needed
  • Suitable for adults aged 16 and over
  • Available without a prescription
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Trusted Short-Term Relief for Occasional Sleeplessness

Nytol® One-A-Night is a clinically proven over-the-counter sleep aid containing diphenhydramine hydrochloride 50mg, an antihistamine with sedative properties. It helps you fall asleep faster and promotes undisturbed rest, making it ideal for occasional sleep disturbances, travel-related jet lag, or stress-related sleeplessness.

What Does Nytol One-A-Night Help With?

Nytol One-A-Night is designed to support:

  • Difficulty falling asleep
  • Waking frequently during the night
  • Short-term sleep issues due to stress or jet lag
  • Restlessness before important events or after travel

The active ingredient, diphenhydramine, blocks histamine receptors in the brain to promote drowsiness and a restful night’s sleep.

Who Is Nytol Suitable For?

  • Adults aged 16 and over with occasional sleeplessness
  • Those struggling with sleep during stressful periods or travel
  • Individuals wanting a non-habit-forming sleep aid

Not suitable if you:

  • Are allergic to diphenhydramine or other antihistamines
  • Have breathing issues (e.g. asthma, sleep apnoea)
  • Have prostate problems or glaucoma
  • Are pregnant or breastfeeding

How to Take Nytol One-A-Night

  • Take 1 tablet around 20 minutes before bed
  • Swallow whole with water
  • Do not exceed 1 tablet in 24 hours
  • Not for use beyond 7 consecutive nights without medical advice

Possible Side Effects

  • Like all medicines, Nytol may cause side effects, including:
  • Dry mouth or throat
  • Headache or mild confusion (rare)
  • Urinary retention (in some individuals)

Avoid alcohol and do not drive or operate machinery after taking.

Why Choose MediClick Pharmacy?

  • Genuine Nytol® One-A-Night from UK-regulated suppliers
  • Convenient one-tablet nightly formula
  • Ideal for jet lag and occasional sleeplessness
  • No prescription required
  • Fast, discreet delivery across the UK
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How It Works

Step - 1

Complete a quick online consultation

Step - 2

Our UK-based prescribers review your application

Step - 3

Once approved, your treatment is dispatched for next-day delivery